Alzheimer’s Harder to Detect in Elderly

  

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A new study suggests that symptoms of Alzheimer’s may be harder to detect in patients over the age of 80. The study tested the relationship between age-related brain shrinkage and Alzheimer’s correlated memory loss. It used just over 100 Alzheimer’s patients and 125 dementia-free people who were grouped by age.

These participants then underwent a series of brain tests with scans that looked at attention, information processing speed and memory.

“People in both groups had similar levels of overall cognitive impairment, but the pattern of changes associated with Alzheimer's disease seemed to be less noticeable in very-old patients than in the young-old”[1].

Compared to other younger patients, the immediate memory and processing speed in very old Alzheimer’s patients was less abnormal indicating that it may be harder to diagnose. 

The study also demonstrated that 80+ Alzheimer’s patients had less thinning of certain areas of the cerebral cortex and cerebellum than the younger patients. This also supports the “hard to diagnose” conclusion because thickness of these brain areas decreases in everyone with age so the differences aren’t as noticeable.